i-gel® from Intersurgical: clinical evidence listing

A comprehensive list of all known published clinical evidence on the device

Endotracheal intubation versus supraglottic airway placement in out-of-hospital cardiac arrest: a meta-analysis

Benoit et al. Resuscitation. 2015 Aug;93:20-6

A literature search was carried out in PubMed, Scopus, and the Cochrane database. Studies where intubation and SADs were compared in prehospital cardiac arrest patients were found and a meta-analysis was carried out. Outcomes measured were ROSC, survival to hospital admission, survival to hospital discharge, and neurologically intact survival until discharge.

Link to abstract

 

Addressing the challenges of paramedic recruitment and engagement in Airways-2

Pilbery R, Green J, Hall H, Whitley G. Emerg Med J 2016; 33e12

Report into the three main challenges facing recruitment for the Airways-2 trial (comparison of i-gel against tracheal intubation in patients suffering OHCA). 

Link to abstract.

Design and implementation of the AIRWAYS-2 trial

Taylor J, Black S, Brett S, Kirby K, Nolan JP, Reeves BC, Robinson M, Rogers CA, Scott LJ, South A, Stokes EA, Thomas M, Voss S, Wordsworth S, Benger JR. Resuscitation. 2016 Sep 30. pii: S0300-9572(16)30476-2

Patient enrollment began in June 2015 for this study comparing the use by paramedics of the i-gel against endotracheal intubation in OHCA in the UK. The primary outcome is the modified Rankin Scale score at hospital discharge. The trial will enrol 9070 patients over two years.

Link to abstract.

Airway management in out-of-hospital cardiac arrest in Finland: current practices and outcomes

Hiltunen P, Jäntti H, Silfvast T, Kuisma M, Kurola J. Scand J Trauma Resusc Emerg Med. 2016; 24: 49

Data on patients with OHCA and attempted resuscitation in an area of Finland over a six-month period in 2010 was collected, with airway techniques and adverse events recorded. Of the 614 patients, 67% were treated with endotracheal intubation and 30% with supraglottic airway devices.  Overall survival to hospital discharge was 17.8%.

Link to abstract

Randomised comparison of the effectiveness of the laryngeal mask airway supreme, i-gel and current practice in the initial airway management of out of hospital cardiac arrest (REVIVE-Airways): a feasibility study

Benger J, Coates D, Davies S, Greenwood R, Nolan J, Rhys M, Thomas M, Voss S. Br J Anaesth. 2016;116(2):262-8

A cluster randomised trial of paramedics within one ambulance service in England over a 12-month period, split into groups using either the i-gel or LMA Supreme or usual practice for all patients with non-traumatic adult OHCA. Primary outcome was study feasibility, including recruitment and protocol adherence. Secondary outcomes included survival to hospital discharge and to 90 days. 184 of 535 paramedics consented, with 615 patients recruited. The LMA Supreme arm was suspended following 'adverse incidents'. No differences were reported in secondary outcomes.

Link to abstract