i-gel® from Intersurgical: clinical evidence listing

A comprehensive list of all known published clinical evidence on the device

Neonatal resuscitation using a laryngeal mask airway: a randomised trial in Uganda

Pejovic N, Trevisanuto D, Lubulwa C, Myrnerts Höök S, Cavallin F, Byamugisha J,  Nankunda J, Tylleskär T. Arch Dis Child. 2018 Mar;103(3):255-260.

This phase two, single-centre, prospective, open-label RCT was carried out at the Mulago National Referral Hospital (Uganda) to assess and compare the safety and performance of the i-gel vs. the face mask (FM) during neonatal resuscitation. 50 patients were randomly assigned into two groups, the i-gel (n=25) and the FM group (m=25). Results showed that the total ventilation time was shorter in the I-gel group compared to the FM one mean 93 vs. 140s, p=0.02). All interventions were successful in the I-gel group, but 11 patients from the FM group were transferred to the I-gel one after 150s. In addition, the mean time to spontaneous breathing was 153s (SD59) with the I-gel and 216s with the FM (SD92) (p=0.005). The study estimated a 31% (95%CI 11 to 44%) reduction in spontaneous breathing when using i-gel. No adverse events were reported when using i-gel (e.g. laryngospasm, bleeding or vomiting), but two patients suffered hypoxic ischaemic encephalopathy in the FM group, and one died within the first 48 hours of life. Thus, the use of a cuffless LMA device may help in reducing the time of spontaneous breathing in neonatal resuscitation compared to FM devices.

Link to abstract.

I-gel O2 resus pack, a rescue device in case of severe facial injury and difficult intubation

Baratto F, Gabellini G, Paoli A, Boscolo A. Am J Emerg Med. 2017 Jan 26

Report of two cases of attempted suicide by firearm managed with the use of the i-gel O2 Resus Pack. In both patients, laryngoscopy attempts failed before an i-gel was inserted and either fibreoptic-assisted intubation or fibreoptic bronchoscopy were performed. Authors conclude that the i-gel's properties mean the device could easily be used by untrained rescuers and might perform an important role during out-of-hospital emergency.

Link to abstract.

i-gel as alternative airway tool for difficult airway in severely injured patients

Häske D, Schempf B, Niederberger C, Gaier G. Am J Emerg Med. 2016;34(2):340

Report of two cases where i-gel was successfully used in a prehospital setting on patients with severe head and neck trauma. Authors suggest that, on evidence, i-gel is an 'appropriate primary airway tool'.

Link to abstract

Comparison of three supraglottic airway devices for airway rescue in the prone position: A manikin-based study

Gupta B, Gupta S, Hijam B, Shende P, Rewari V. J Emerg Trauma Shock. 2015 Oct-Dec;8(4):188-92

Insertion of i-gel, ProSeal and LMA Classic were studied in prone position. Time to insertion, ease of insertion, bronchoscopic view an insertion score were compared. i-gel was the quickest and easiest to insert.

Link to abstract

Emergency airway management by paramedics: comparison between standard endotracheal intubation, laryngeal mask airway, and I-gel

Leventis C, Chalkias A, Sampanis MA, Foulidou X, Xanthos T. Eur J Emerg Med. 2014 Oct;21(5):371-3

72 briefly-trained paramedics were allocated to intubate a manikin. Success rate was higher, and insertion time 'significantly' shorter for the i-gel group.

Link to abstract