i-gel® from Intersurgical: clinical evidence listing

A comprehensive list of all known published clinical evidence on the device

Analyzing the efficacy of the I-gel supraglottic airway device in supine and lateral decubitus position

Saracoglu KT, Demir A, Pehlivan G, Saracoglu A, Eti Z. Anaesthesiol Intensive Ther. 2018 Sep 17

This prospective clinical trial assessed and compared the airway leak pressure and the fiberoptic view of the i-gel in both supine and lateral positions. Moreover, the impact of the i-gel insertion on haemodynamics was also monitored. 100 patients undergoing saturation biopsy were intubated with the i-gel in the supine position, which was subsequently changed to lateral position. Several measurements were taken after intubation and change of position, which included mean arterial pressure, heart rate, peripheral O2 saturation and end-tidal CO2. Furthermore, number of insertion attempts, insertion time, oropharyngeal leak pressure (OLP), and device placement were also recorded. The i-gel was successfully inserted in 88 patients on the first attempt and the insertion time was circa 8 seconds. Moreover, the OLP (27.45 mm Hg supine and 26.04 in lateral position) and fiberoptic view were comparable in both positions. Hence, the i-gel can be safely employed in both supine and lateral positions.

Link to abstract.

Non-Conventional Utilization of the Aintree Intubating Catheter to Facilitate Exchange Between Three Supraglottic Airways and an Endotracheal Tube: A Cadaveric Trial.

Lopez NT, McCoy SK, Carroll C, Jones E, Miller JA. Mil Med. 2018 Jun 19 [Epub ahead of print]

Prospective crossover study on cadavers to measure airway exchange on three pre-placed supraglottic airways: King LT, i-gel and LMA Unique. Participants, recruited from emergency medical personnel in a training lab, rated the difficulty level of placement of each airway device. Successful exchange equalled proper placement of the ETT in the trachea. Authors conclude the i-gel superior for blind airway exchange with an ETT in this set up.

Link to abstract.

Current practice patterns of supraglottic airway device usage in paediatric patients amongst anaesthesiologists: A nationwide survey.

Jain RA, Parikh DA, Malde AD, Balasubramanium B. Indian J Anaesth. 2018 Apr;62(4):269-279

This survey was sent to over 16,000 members of the Indian Society of Anaesthesiologists and given to delegates at the Asian Society of Paediatric Anaesthesiologists conference 2017. Percentage, mean and standard deviation were calculated. Results showed i-gel was the most commonly used device (60%) and 75% of respondents had access to second-generation supraglottic airways.

Link to abstract.

Neonatal resuscitation using a laryngeal mask airway: a randomised trial in Uganda

Pejovic N, Trevisanuto D, Lubulwa C, Myrnerts Höök S, Cavallin F, Byamugisha J,  Nankunda J, Tylleskär T. Arch Dis Child. 2018 Mar;103(3):255-260.

This phase two, single-centre, prospective, open-label RCT was carried out at the Mulago National Referral Hospital (Uganda) to assess and compare the safety and performance of the i-gel vs. the face mask (FM) during neonatal resuscitation. 50 patients were randomly assigned into two groups, the i-gel (n=25) and the FM group (m=25). Results showed that the total ventilation time was shorter in the I-gel group compared to the FM one mean 93 vs. 140s, p=0.02). All interventions were successful in the I-gel group, but 11 patients from the FM group were transferred to the I-gel one after 150s. In addition, the mean time to spontaneous breathing was 153s (SD59) with the I-gel and 216s with the FM (SD92) (p=0.005). The study estimated a 31% (95%CI 11 to 44%) reduction in spontaneous breathing when using i-gel. No adverse events were reported when using i-gel (e.g. laryngospasm, bleeding or vomiting), but two patients suffered hypoxic ischaemic encephalopathy in the FM group, and one died within the first 48 hours of life. Thus, the use of a cuffless LMA device may help in reducing the time of spontaneous breathing in neonatal resuscitation compared to FM devices.

Link to abstract.