i-gel® from Intersurgical: clinical evidence listing

Byon HJ, Song J, Shinn HK, Song K, Lee C, Lim H. Minerva Anestesiol. 2016 Sep;82(9):950-6

Patients were randomly assigned to either the i-gel or intubation group and induced using propofol or sevoflurane. Peak QTc interval was lowever in the i-gel group. Authors conclude the i-gel 'may be advantageous' to patients at risk of QTc prolongation.

Link to abstract

Choi JB, Kwak HJ, Lee KC, Lee SR, Lee SY, Kim JY. J Anesth. J Anesth. 2016 Jun;30(3):377-83

Randomised study comparing 41 female patients across two groups: i-gel and LMA, undergoing anaesthesia. EC50 of remifentanil concentration for i-gel insertion was significantly lower.

Link to abstract

Choi JJ, Kim JY, Lee D, Chang YJ, Cho NR, Kwak HJ. BMC Anesthesiol. 2016 Mar 22;16:20

40 patients were split into equal gender groups prior to insertion. The EC50 of propofol in men was approximately 40% higher than in women. Gender should be considered when determining optimal dose of propofol, according to the authors.

Link to abstract

Ashay NA, Wasim S, Anil TB. J Anaesthesiol Clin Pharmacol. 2015 Jul-Sep;31(3):324-8

This randomised controlled trial compared propofol requirements for i-gel and LMA Classic when inserted 60 seconds after injection. i-gel required a significantly lower dose.

Link to abstract

Jang YE, Kim YC, Yoon HK, Jeon YT, Hwang JW, Kim E, Park HP. J Anesth. 2015 Jun;29(3):338-45

37 patients were randomly allocated to either a dexmedetomidine or control (saline) group. Authors conclude that preoperative dexmedetomidine reduced the EC50 of propofol.

Link to abstract